Background

Physical imaging phantoms for quality control and research in the field of Magnetic Resonance Imaging (MRI) are mostly composed of polymers as PMMA or alike. For combined Positron Emission Tomography (PET) /MRI systems (PET/MR), these materials lead to a problem related to the attenuation correction for the correct quantification of the PET-tracer emitting photons, since the solid polymers are not visible in MRI. Furthermore, for MRI phantoms, liquid fillings or gelatin-based compartments as the signal producing parts of the phantoms limit their long term stability.Therefore, development of new materials visible in MRI is currently needed.

Technology Overview

The technology uses micro-particles, which absorb the used proton-rich fluid and keep it inside the mixture with acrylic resins. We have developed a light-curable resin composition capable of producing an MRT imaging-signal, in particular for lithography-based additive production of MRI phantoms.

The ratio between the particles and the used fluid can be adjusted to obtain different MR signal and contrast properties. Also problems related to reproducibility, stability and turbulent flowings of the phantom liquids like no down-settling after positioning for general MRI phantoms can be avoided. Further, this UV-curable MRI visible resin can be used in combination with 3D printing for an easy production of MRT visible test objects.

Benefits

Can be used to produce PET/MR phantoms
Usable for MR-phantoms instead of liquids for avoiding flowing artefacts, improve reproducibility and long term stability
No Segregation when mixed with fluids
Can be used to produce support devices for PET/MRI diagnostics and radio therapy applications for fixation devices when using MRI for therapy planning
Mimicking of different human tissues possible

Applications

PET/MR imaging phantoms

Opportunity

Cooperation /License agreement

Novel 3D Printable Phantoms for Medical Imaging

Patents

IP Status

Seeking